Background:Finasteride (brand name Propecia) is a medication that blocks the action of 5-alpha-reductase in the body. The drug can affect the liver and prostate, causing symptoms such as hair loss, erectile dysfunction, and decreased semen volume. In a clinical study, the drug was found to increase the risk of prostate cancer. Therefore, the drug has been used in the treatment of prostate cancer and is now available for use in the treatment of male pattern hair loss. We present a case of prostate cancer induced by a drug that inhibits 5-alpha-reductase from activating the enzyme in the body.
Case presentation:A 30-year-old male was diagnosed with a benign prostatic hyperplasia (BPH) prostate. He was taking Propecia, a 5-alpha reductase inhibitor, which blocks the action of the enzyme 5-alpha-reductase. He had experienced an initial TURP, which was diagnosed 3 months before the start of the 5-alpha reductase inhibitor. Propecia is a prescription drug and the 5-alpha reductase inhibitor, which inhibits the enzyme and blocks the conversion of testosterone to dihydrotestosterone (DHT) in the body. The drug inhibits the enzyme and the conversion of testosterone into DHT is decreased in the prostate. The clinical response of the patient to Propecia was not satisfactory. The patient had a 4-year history of erectile dysfunction, which was not diagnosed until the diagnosis of BPH in October 2009. He had been taking Propecia for 3 months before his start in the first year of the 5-alpha reductase inhibitor therapy. He had experienced erectile dysfunction 3 months before starting Propecia and a few times a year before the start of the 5-alpha reductase inhibitor therapy. He had a prostate biopsy that was negative for prostate cancer. He had an evaluation for prostate cancer at the age of 39 years. He was diagnosed with prostate cancer in March 2010.
Discussion:This case presents a patient who was prescribed Propecia for BPH in October 2009. The 5-alpha reductase inhibitor was not effective in preventing prostate cancer. The patient's prostate biopsy was negative for prostate cancer. He had no other comorbidities. It was not surprising that he was prescribed the drug for BPH in October 2009, but the drug could not be removed. It is possible that the drug could have a similar effect on the prostate, which may affect the treatment response of the patient. The drug was not effective in preventing prostate cancer or decreasing the quality of life of the patient. This case is not surprising given the fact that the 5-alpha reductase inhibitor was not effective in preventing prostate cancer and Propecia was not effective in preventing prostate cancer.
Conclusion:This patient is a 30-year-old male with no other comorbidities. The 5-alpha reductase inhibitor was effective in preventing prostate cancer and Propecia was not effective in preventing prostate cancer. There is no evidence to support a causal relationship between Propecia and prostate cancer. Propecia may be used for the treatment of male pattern hair loss and the drug could be used to treat male pattern hair loss by inhibiting the enzyme. This case report provides the first case of Propecia/finasteride-associated prostate cancer treated with the drug.
Al- Samean W, et al. (2013) Prostate cancer drug-induced prostate cancer. PLoS ONE 8(8): e100769. https://doi.org/10.1371/journal.pone.100769Editor:Meyad Ahmed Al-Araa, University of Wisconsin Madison, USA
Received:June 15, 2013;Accepted:September 4, 2013;Published:October 5, 2013
Copyright:© 2013 Samean et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability:The patient's medical records of the patients who participated in the Propecia trial were reviewed. The case report is included within the file of the original manuscript.
Finasteride is a non-steroidal aromatase inhibitor (AIs) drug used to treat male pattern hair loss (androgenetic alopecia) and benign prostatic hyperplasia (BPH). It works to shrink and stop the conversion of testosterone into dihydrotestosterone (DHT) which is a potent killer for hair follicles. Finasteride is used to prevent hair loss in women who have male pattern hair loss.
Finasteride is a generic medication prescribed by doctors for the treatment of hair loss and balding in men and women. It is available in various strengths, and is commonly used to treat the symptoms of benign prostatic hyperplasia (BPH) and male pattern hair loss (androgenetic alopecia).
Finasteride is the brand name for the drug finasteride, which belongs to a class of drugs called 5-alpha reductase inhibitors. Finasteride is known by the brand name Propecia, while Proscar is a generic version of the drug.
Finasteride tablets are taken once a day, preferably on an empty stomach, or at approximately the same time of day as the night before bedtime. The recommended starting dose of Finasteride is 1 mg, taken as needed, but this can be increased up to 5 mg or decreased to 1 mg. This dosage is based on your medical condition and response to treatment.
Finasteride tablets may be taken with or without food. If you have heavy or fatty meals before taking this drug, it is advised to take it at a fixed time each day so that the drug does not interfere with your daily routine. Do not take it more often than once every 24 hours (or as directed by your doctor).
Finasteride tablets should not be taken by women who are pregnant or breastfeeding. It may harm your unborn baby. It may also increase the risk of certain eye conditions, especially retinitis pigmentosa (an inherited eye condition that causes loss of vision in one eye).
If you are taking finasteride and notice unusual tiredness or weakness on one side of the body, particularly if you do not feel better soon after taking this, please consult your doctor. Do not drive or operate machinery until you know how this affects you.
The most common side effects of finasteride are decreased libido, erectile dysfunction, and ejaculation disorder (an increase in male ejaculate volume that causes thinning of the penis or pain in the testicles). These side effects usually resolve on their own within a few days or weeks. However, if the side effects last longer or get worse, please speak with your doctor or pharmacist for advice.
The most common side effects of Propecia are headache, breast tenderness, acne, and changes in the breast tissue.
The most common side effects of Proscar are mood changes, breast tenderness, acne, and changes in the breast tissue.
The recommended starting dose is 1 mg, taken as needed, but this can be increased up to 5 mg or decreased to 1 mg.
Do not take this drug if you are pregnant or breast-feeding.
If you miss a dose of Finasteride, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Dr. B. O. Cis an endocrinologist who has worked in men suffering from benign prostatic hyperplasia (BPH), a condition in which the prostate gland enlarges. He has a special interest in the management of male pattern baldness, with particular focus on the treatment of BPH. He has a special interest in the treatment of male pattern baldness with alpha-blockers and DHT (diethylene triamine oxidase inhibitors) which are used in the treatment of prostate cancer. He has a particular interest in the treatment of male pattern baldness with alopecia areata (AAN), which is a disorder of the hair follicles which causes thinning hair. He also has a particular interest in the treatment of hair loss in balding patients. He is a specialist in the management of hair loss, particularly in the areas of the crown and middle back and has been treating patients with balding for several years. He is an active member of the Alopecia Hair Restoration Program. He has been involved in a number of clinical studies and has received numerous recommendations from the medical community to improve the appearance of the male pattern baldness and to promote the healing of the hair follicles.
In the past, men had a baldness at the front of the scalp, usually as a result of a hereditary condition called alopecia areata (AGA). This condition is now very common and affects millions of men worldwide. Alopecia areata can be triggered by many different factors, some of which can cause significant hair loss and can lead to baldness in the head, scalp, or the back of the head. The alopecia areata condition is the most common hair loss in men. There are a number of treatments available for hair loss and there are some who have shown some success using alopecia areata in clinical trials. However, there are also treatments available which can help to prevent or reverse the symptoms of alopecia areata. These include treatments such as DHT (diethylene triamine oxidase inhibitors), which can be prescribed by a specialist such as a surgeon or dermatologist. The alopecia areata treatment may be used to treat a number of other conditions, including BPH, to treat male pattern baldness. This includes the treatment of hair loss in the back of the head. For some people, the treatment may be a solution to a balding condition. It can also be used to treat other conditions that cause hair loss, such as alopecia areata. The treatment of hair loss in the back of the head is also known as the balding treatment, or the treatment of balding in the front of the head. This type of hair loss is called alopecia areata. It is important to note that the alopecia areata will not be reversed by hair transplantation.
The treatment of hair loss in the back of the head will only be effective if the patient is healthy and does not have balding. There are two types of treatment. The treatment of hair loss in the front of the head will only be effective if the patient is healthy and does not have balding. There are also two types of treatments for hair loss, which are called alopecia areata and finasteride (DHT). Finasteride is an oral medication that is used to treat men who have a receding hairline or thinning on the scalp. It can be used to treat male pattern baldness. It works by blocking the effects of a hormone called DHT, which is an important factor in the development of hair loss in men. Finasteride works by blocking the effects of the hormone DHT, which is known as the DHT hormone in the scalp. The effectiveness of finasteride is thought to be based on the fact that it works by reducing the production of DHT. The effects of finasteride on hair loss in men have not been studied and there are no studies in the men. It is also unknown whether finasteride works by decreasing the amount of DHT that is produced in the scalp. This is because finasteride has been shown to be more effective than either of the hair loss treatments listed above. A recent study, which was published in the Journal of the American Academy of Dermatology, showed that using finasteride is more effective than using the alopecia areata treatments.
The most common side effects of Propecia include a decreased interest in sexual intercourse, inability to have or keep an erection, or a loss in sexual ability, desire, drive or performance. Talk to your doctor or a healthcare professional if you experience these side effects, and they may be related to your medical condition.
In addition, you should know that Propecia can help you to reduce the risk of developing bladder cancer. Talk to your doctor if you have any risk factors for prostate cancer or if you'rephilis tested positive for prostate bacteria. Finally, you should know that Propecia is used to treat prostate glandnon-cancer conditions (benign prostatic hyperplasia, adenomyosis, and extra-urethral noncancerous smooth muscle disease).
If you are taking any other medicines, please consult your doctor, especially if you are taking or have recently taken any other medicines.
Please note that Propecia is not addictive. It is intended for use by men and women as well as children and breastfeeding women.
If you are suffering from kidney disease or kidney problems, please consult your doctor. It is better to consult your doctor for more details.
Medication information| Medication name | Information | Details |
|---|---|---|
| Propecia (finasteride) | Male pattern hair loss (MPHL) | 1mg |
| 2mg | ||
| 3mg | ||
| 4mg | ||
| 5mg | ||
| 6mg | ||
| 7mg | ||
| 8mg | ||
| 9mg | ||
| 10mg | ||
| 11mg | ||
| 12mg |
Please consult your doctor.
Propecia (finasteride) is used to treat male pattern hair loss (MPHL).
In addition to taking Propecia, Propecia may affect the developing fetus, the birth control pill, the effect of pregnancy, and the development of breast cancer. If you are pregnant or plan to become pregnant, please consult your doctor. Propecia passes into breast milk and may affect your baby. Propecia should be used during pregnancy only if the benefits outweigh the risks.
It is intended for use by men and women as well as children and adolescents.
If you are suffering from kidney disease or kidney problems please consult your doctor. Talk to your doctor if you are taking any of the medicines listed above.
If you are breastfeeding, please consult your doctor.
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